Selection of a HER2/Neu Specific scfv by Ribosome Display for Targeting of HER2/Neu Positive Cancers
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چکیده
منابع مشابه
Selection of single-chain variable fragments specific for Mycobacterium tuberculosis ESAT-6 antigen using ribosome display
Objective(s): Tuberculosis (TB) is still one of the problematic infectious diseases in developing countries, especially in Iran. In the present study, we applied ribosome display technique to select single chain variable fragments (scFvs) specific for the 6-kDa early secretory antigenic target (ESAT-6) antigen of Mycobacterium tuberculosis from a mouse scFv library. Materials and Methods: The g...
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Ribosome display was applied in vitro to select single-chain variable fragment (scFv) antibody specific for digoxin from a human non-immune naive scFv library. A cell-free system was used to produce stable antibody-ribosome-mRNA (ARM) complexes to provide the linkage of genotype and phenotype, allowing simultaneous selection of a desired antibody together with its encoding mRNA. The mRNA was th...
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Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection
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ژورنال
عنوان ژورنال: Multidisciplinary Cancer Investigation
سال: 2017
ISSN: 2476-4922
DOI: 10.21859/mci-supp-54